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Wednesday, November 20 • 10:40am - 11:00am
Enabling Drug Discovery:Target Validation to PreClinical- Establishing Small Molecule Discovery at the Cleveland Clinic Lerner Research Institute

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This presentation will discuss the newly formed Cleveland Clinic Center for Therapeutics Discovery (C3TD), its mission, model, and current status towards building a modern compound management and screening facility for investigators at the Lerner Research Institute.  At C3TD we embrace the strategic plan supporting our founder’s unifying three pillar mission:  care for the sick, investigate their problems, and educate our community. To be successful in contributing to our shared mission, assembled project teams leverage the most innovative approaches currently being explored for the treatment of human diseases and disorders and ‘de-risk’ to a point where these treatment strategies can directly impact patient care. By integrating high performance drug discovery resources and teams in the Lerner Research Institute, medicinal chemistry, molecular pharmacology, biochemistry, structural sciences, and drug metabolism and pharmacokinetics (DMPK) disciplines work together to illuminate and advance scientific breakthroughs beyond the traditional academic lab towards useful chemical probes and IND-ready assets.  Robust proven technologies in conjunction with best practices and protocols will be discussed in context of successes and lessons learned in prior academic drug discovery endeavors in neuroscience and oncology.

avatar for Shaun Stauffer, Ph.D.

Shaun Stauffer, Ph.D.

Director, Cleveland Clinic Center for Therapeutics Discovery, Cleveland Clinic
Dr. Stauffer directs the newly formed Cleveland Clinic Center for Therapeutics Discovery initiated in 2018. He obtained his Ph.D. in organic chemistry 1999 from the University of Illinois Urbana-Champaign under John Katzenellenbogen and did post-doctoral studies with John Hartwig... Read More →


Marybeth Burton

Executive Director, Discovery Sample Management, Merck

Wednesday November 20, 2019 10:40am - 11:00am EST
Essex South (3rd Floor) - Westin Copley 10 Huntington Avenue, Boston, MA 02116 USA

Attendees (1)